Calcium Dynamics Model Atlas

Scope audit

Relevant means mechanistically connected

The prior broad bone-model list was narrowed. Genetics, estrogen-only BMD, fatigue, mechanics, and spatial models are not shown because they do not simulate mineral dynamics.

What the atlas now includes

Direct models have calcium or phosphate states, fluxes, endocrine feedback, or calcium-focused clinical outputs. They cover gut absorption, renal handling, parathyroid control, calcitriol, FGF23, bone mineral exchange, CKD-MBD, and hypoparathyroidism.

Supporting mechanisms are retained only where PTH-controlled bone resorption/formation provides a direct biological bridge to calcium mobilization and is part of the Peterson–Riggs lineage. The cards state plainly when serum calcium is not explicit.

Start with physiology

Where the retained models sit

Choose a compartment to filter the atlas. Solid arrows indicate mineral/endocrine flows; dashed arrows are feedback.

mineral or endocrine flowfeedback/signaling

Explore the literature

Choose a calcium-relevant model

9 models shown

Model role

Physiology

Selected model

Physiological interpretation

“Supporting” does not mean a calcium state is hidden: it means the card identifies its precise PTH-to-bone role and its limitation.

Comparison matrix

What is explicit in each model?

Rows use the same clinical-physiology dimensions. Click a row to inspect the model.

Model	Role	Ca / PO4	Endocrine	Kidney	Bone cells	Outputs	Julia